How are you suppose to reply to はじめまして

[-悪魔-]

Whats the appropiate reply when someone says that to you?

[jonny-mt]

You can reply back with はじめまして...it basically translates to "nice to meet you" and is used in a fashion similar to English. Since the person is introducing themselves to you, it would be rude of you to not do the same in return.

[-悪魔-]

But I thought はじめまして was "How do you do?"

And whats the difference between はじめまして and どうぞ宜しく?

[PaulTB]

But I thought はじめまして was "How do you do?"
Not really. The nearest to "How do you do?" is お元気ですか。"

[Elizabeth]

There are several possiblities, but something alone these lines should do.

Hajimemashite. (Your name desu.) (Kochirakoso.) Douzo yoroshiku (onegaishimasu.)